Advances in Gene Therapy Treatment for Obesity: A Mini-review

Abstract

Obesity is a highly prevalent global pandemic that is rapidly growing. Recent advancements in gene therapy have opened
new possibilities and targets for treating, especially monogenic forms of obesity. This mini-view identified novel preclinical
developments in obesity genetic treatment over the past five years. Novel strategies targeting single or multiple genes or
enzymes were identified as potential alternatives for existing treatment approaches. Although clinical trials for genetic
obesity treatment are yet to emerge, novel preclinical treatment approaches based on genetic traits hold promise for addressing
the obesity pandemic.