Impact of Rising Global Temperatures on Dengue Infection and Serotype Distribution: A Mini Review

Main Article Content

Staling Guillermo Pallares Escorcia
Claudia Gonzalez
Alaa Ali
Alfredo Gabriele Nanni
Ana Luíza Soares Pinto
Bruno Meireles de Moraes
Carol Arce Sanjur
Caroline Borginho
Cristal N. Pride
Einer C.E. Arevalo-Rios
Erwin León
Glauco Marinho Plens
Hiroshi Hayashi
Jose Max Narvaez Paliza
Justyna Garnier
Karina Gisell Duerksen Crespo
Keila Miranda-Limachi
Kelvin Henrique Vilalva
L. Angie Paucar Cisneros
Luiza Lara Gadotti
Mariana Pilon Capella
Mitha Al Balushi
Patricio A. Alfaro
Pedro Slindvain Freitas
Roksana Hasib
Ruan Pablo Duarte Freitas
Sibin Marian
Victoria Gomes Andreata
Supattana Chatromyen

Abstract

Background: Dengue virus (DENV) infection is currently one of the most significant vector-borne viral diseases in
terms of global morbidity and mortality. Climate change studies have demonstrated the association between dengue virus
transmission and variations in ambient temperature. We performed a mini-review to evaluate whether there are differences
in the association between the increase in ambient temperature and the incidence of dengue among the different dengue
serotypes.

Methods: For this systematic review we searched MEDLINE and PubMed databases for studies published within the last
15 years, from database inception to the execution of this review, focusing on the association between dengue incidence of
serotypes and temperature variations globally. We excluded studies that involved reviews, modeling with only prospective
data, prediction, or predictive models. The quality of the evidence was assessed using the Newcastle-Ottawa Scale (NOS).

Findings: There is a significant association between temperature and DENV infection due to global warming. No specific
dengue serotypes were identified as predominant in the reviewed studies. Aedes aegypti and Aedes Albopictus, the primary
dengue vectors of DENV, have different behaviors in response to temperature changes.

Discussion: The findings of this review emphasize the strong relationship between temperature and dengue incidence. Expanding the geographical scope and including more prospective studies would enhance the understanding and generalizability
of these findings.

Conclusion: This review showed a significant relationship between temperature increases (in the context of global warming)
and dengue infection, leading to potential outbreaks. A more thorough analysis of serotypes is recommended for future
studies. 

Article Details

How to Cite
Impact of Rising Global Temperatures on Dengue Infection and Serotype Distribution: A Mini Review. (2025). Principles and Practice of Clinical Research, 10(3). https://doi.org/10.21801/ppcrj.2024.103.6
Section
View and Review

How to Cite

Impact of Rising Global Temperatures on Dengue Infection and Serotype Distribution: A Mini Review. (2025). Principles and Practice of Clinical Research, 10(3). https://doi.org/10.21801/ppcrj.2024.103.6

Most read articles by the same author(s)