Effectiveness of Remote Mindfulness Interventions in Reducing Depressive Symptoms During Pregnancy and the Postpartum Period: A Systematic Review and Meta-analysis

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Maria Yemane
Tadeus Luis Lopez Ulloa
Alvaro Lopes de Oliveira
Amanda Querino Andrade Viana
Andrea Siles De La Portilla
Bruno César Rodrigues do Amaral
Daniela Lorena Alvarado Rodriguez
David Abalovich
Débora Pinheiro Xavier
Fabiane Barbero Klem
Federico Antillon-Klussmann
Gabriela Coelho Itaya
Gabriella Bezerra dos Santos
Harsh Vardhan Chawla
Isabela Castaneda
Issbah Rma
Johan Antonio De La Rosa Laureano
Luca Ferrari
Lucas Fernando Uratani
Marcia Beatriz Oliveira de Sousa
María Alejandra Garza Ledezma
Matías Deck Labra
Miguel Miranda
Nadine Alejandra Aranis Seguic
Rodas Annose
Rodrigo Pegado
Salvatore Minnella
Seunghyun Kim
Sofia Teixeira Prates de Oliveira
Yasmin Azevedo Elias
Yazmin Alejandra Heredia Allegretti

Abstract

Aim: This systematic review examines the effectiveness of mobile and remote mindfulness interventions in reducing depression symptoms during pregnancy and the postpartum period.


Background: Postpartum depression is highly prevalent in women and can contribute to up to 20% of maternal mortality, affecting the health of both mother and child. Effective treatment is a challenge, and a growing number of studies show that mobile and remote mindfulness interventions are potential new interventions.


Design: A systematic review and meta-analysis.


Methods: A comprehensive search was conducted in PubMed and Cochrane Library on May 4th, 2024, investigating randomized controlled trials in pregnant women. A meta-analysis was performed on seven studies assessing the impact of remote mindfulness interventions on depression symptoms measured with the Edinburgh Postnatal Depression Scale (EPDS).


Results: A total of 997 studies were screened, with 7 studies included in the final analysis. A meta-analysis of four studies on the reduction of EPDS scores immediately post-intervention was conducted. Significantly lower EPDS scores were observed in the intervention group compared to the control group (mean difference -1.93; 95% CI -3.78 to -0.08; P = 0.04, I² = 81%, P < 0.01; high heterogeneity). A second meta-analysis on the persistence of effects through the postpartum period showed no significant differences between the groups (mean difference -2.63; 95% CI -6.13 to 0.86; P = 0.14, I² = 91%, P < 0.01; high heterogeneity).


Conclusion: Mindfulness interventions delivered through mobile health applications have the potential to prevent depressive symptoms during pregnancy and the postpartum period.

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How to Cite
Effectiveness of Remote Mindfulness Interventions in Reducing Depressive Symptoms During Pregnancy and the Postpartum Period: A Systematic Review and Meta-analysis. (2025). Principles and Practice of Clinical Research, 11(1). https://doi.org/10.21801/ppcrj.2025.111.3
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How to Cite

Effectiveness of Remote Mindfulness Interventions in Reducing Depressive Symptoms During Pregnancy and the Postpartum Period: A Systematic Review and Meta-analysis. (2025). Principles and Practice of Clinical Research, 11(1). https://doi.org/10.21801/ppcrj.2025.111.3

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