Maria Yemane
Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Tadeus Luis Lopez Ulloa
Two Oceans in Health, Santo Domingo, Dominican Republic;
Alvaro Lopes de Oliveira
A.C. Camargo Cancer Center, São Paulo, Brazil
Amanda Querino Andrade Viana
Hospital Santo Antônio, Obras Sociais Irmã Dulce, Salvador, Bahia, Brazil
Andrea Siles De La Portilla
Universidad San Martin de Porres, Facultad de Medicina Humana, Lima, Peru
Bruno César Rodrigues do Amaral
Instituto D’or de Pesquisa, São Paulo, Brazil
Daniela Lorena Alvarado Rodriguez
Clinica Alemana, Santiago, Chile
David Abalovich
Universidad de Buenos Aires, Buenos Aires, Argentina
Débora Pinheiro Xavier
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Fabiane Barbero Klem
Sabara Hospital Infantil, São Paulo, Brazil
Federico Antillon-Klussmann
School of Medicine, Francisco Marroquin University, Guatemala City, Guatemala;
Gabriela Coelho Itaya
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Gabriella Bezerra dos Santos
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Harsh Vardhan Chawla
Royal Papworth Hospital, Cambridge, United Kingdom
Isabela Castaneda
Pontificia Universidad Javeriana, Bogotá, Colombia
Issbah Rma
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Johan Antonio De La Rosa Laureano
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Luca Ferrari
Faculdade de Medicina São Leopoldo Mandic, Campinas, São Paulo, Brazil;
Lucas Fernando Uratani
Complexo Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil
Marcia Beatriz Oliveira de Sousa
Hospital Universidade Federal do Maranhão (HUUFMA), São Luís, Maranhão, Brazil
María Alejandra Garza Ledezma
Matías Deck Labra
Clínica Dávila, Santiago, Chile
Miguel Miranda
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Nadine Alejandra Aranis Seguic
Servicio de Medicina Física y Rehabilitación, Clínica Alemana, Universidad del Desarrollo, Santiago, Chile;
Rodas Annose
Addis Ababa University, School of Medicine, Addis Ababa, Ethiopia
Rodrigo Pegado
Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, USA
Salvatore Minnella
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA. Evidence Based Slow Musculoskeletal Medicine Approach Institute (EBaSMMAI), Italy.
Seunghyun Kim
Harvard T. H. Chan School of Public Health - ECPE - PPCR Program, Boston, MA, USA
Sofia Teixeira Prates de Oliveira
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil
Yasmin Azevedo Elias
Yazmin Alejandra Heredia Allegretti
Universidad Autónoma de Yucatán, Facultad de Medicina, Mérida, Yucatán, Mexico
Abstract
Aim: This systematic review examines the effectiveness of mobile and remote mindfulness interventions in reducing depression symptoms during pregnancy and the postpartum period.
Background: Postpartum depression is highly prevalent in women and can contribute to up to 20% of maternal mortality, affecting the health of both mother and child. Effective treatment is a challenge, and a growing number of studies show that mobile and remote mindfulness interventions are potential new interventions.
Design: A systematic review and meta-analysis.
Methods: A comprehensive search was conducted in PubMed and Cochrane Library on May 4th, 2024, investigating randomized controlled trials in pregnant women. A meta-analysis was performed on seven studies assessing the impact of remote mindfulness interventions on depression symptoms measured with the Edinburgh Postnatal Depression Scale (EPDS).
Results: A total of 997 studies were screened, with 7 studies included in the final analysis. A meta-analysis of four studies on the reduction of EPDS scores immediately post-intervention was conducted. Significantly lower EPDS scores were observed in the intervention group compared to the control group (mean difference -1.93; 95% CI -3.78 to -0.08; P = 0.04, I² = 81%, P < 0.01; high heterogeneity). A second meta-analysis on the persistence of effects through the postpartum period showed no significant differences between the groups (mean difference -2.63; 95% CI -6.13 to 0.86; P = 0.14, I² = 91%, P < 0.01; high heterogeneity).
Conclusion: Mindfulness interventions delivered through mobile health applications have the potential to prevent depressive symptoms during pregnancy and the postpartum period.
