Clarissa Bueno
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA.Department of Neurology, University of São Paulo, São Paulo, Brazil
Eline Rozaria Ferreira Barbosa
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Military Police of Goiás State, PPCR student, Valparaíso de Goiás, Brazil
Desiree Rodrigues da Veiga
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hapvida NotreDame Intermédica, São Paulo, Brazil
Hilario de Sousa Francelino
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA.Hospital São Vicente IESA, Iguatu, Brazil
Andrea Suarez Gomez
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA.Fundación Cardio Infantil, Bogotá, Colombia
Ivan Dunshee de A.O. Santos Filho
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. A.C. Camargo Cancer Center, São Paulo, Brazil
Lyna Kyria Rodrigues de Almeida
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Clinical Hospital of the School of Medicine, University of São Paulo, São Paulo, Brazil
Pedro Henrique Martins da Cunha
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Department of Neurology, Clinical Hospital of the School of Medicine, University of São Paulo, São Paulo, Brazil
Erika Bushatsky Andrade de Alencar
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Beneficência Portuguesa de São Paulo, São Paulo, Brazil
Abrahan Salcedo Perez
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Pontificia Universad Católica Madre y Maestra, Santiago De Los Caballeros, Dominican Republic
Chukwuma Eze Okereke
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Federal Medical Centre, Owo, Nigeria
Daniel Gomez-Carrillo
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. University of Los Andes, Bogotá, Colombia
Danny Chris Vinas
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Pontificia Universad Católica Madre y Maestra, Santiago De Los Caballeros, Dominican Republic
Rinna Segatto Siquieroli
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Instituto D'Or de Pesquisa e Ensino (IDOR), São Paulo, Brazil
Agustin N. Posso
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
Victor Barrientos Labra
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hospital del Trabajador - ACHS, Santiago, Chile
Sara Lanaia
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Pontificia Universad Católica Madre y Maestra, Santiago De Los Caballeros, Dominican Republic
Isabella Meneghetti Inacio Silva
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Clinical Hospital of the School of Medicine, University of São Paulo, São Paulo, Brazil
Elmira Mustafayevna Lomashvil
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Mercer University, Macon, USA
Laura Soledad Samudio Sanchez
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Universidad del Pacífico Privada, Asunción, Paraguay
Sebastian Castañon Muñoz
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hospital del Trabajador - ACHS, Santiago, Chile
Priscila Fuentes
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Clínica Dávila, Santiago, Chile
Angelica Sam
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hospital Del Policia, Lima, Peru
Andrea De Góes Trindade Mello
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hospital Universitário Professor Edgar Santos, Federal University of Bahia, Salvador, Brazil
Nicolas Emiliozzi
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hospital Central de San Isidro, Buenos Aires, Argentina
Mayra Gabriela Ayala
Principles and Practice of Clinical Research Program, Executive and Continuing Professional Education (ECPE), Harvard T.H. Chan School of Public Health, Boston, MA, USA. Hospital Metropolitano, Quito, Ecuador
Abstract
Introduction: Sleep disorders can contribute to the development and worsening of depression symptoms. To understand how depression impacts sleep regulation, models are necessary. This study aims to analyze how depression influences sleep patterns.
Methods: A cross-sectional study was conducted using the NHANES 2017-2018 dataset, which included 5.088 adults. The primary outcome was the presence of daytime sleepiness among participants with depressive symptoms (PHQ-9 > 4) compared to participants without depressive symptoms (PHQ-9 ≤ 4). The regression analysis considered the following covariates: age, gender, BMI, and the presence of at least one comorbidity. A secondary analysis examined the severity of depression, BMI > 25, and a history of diabetes or cancer. Statistical analyses were performed using StataNow/BE 18.5.
Results: Participants exhibiting depressive symptoms had a significantly higher likelihood of feeling sleepy during the day (OR 4.39; 95% CI 3.83–5.04; p < 0.001). Univariate analysis revealed statistically significant associations (p < 0.05) for all included variables: Age (OR = 0.99, log-likelihood = -2911.28); Gender (OR = 1.27, log-likelihood = -2907.12); BMI (OR = 1.03, log-likelihood = -2853.69); At least one comorbidity (OR = 1.69, log-likelihood = -2882.59). The final model confirmed a significant association between depressive symptoms and daytime sleepiness (OR 4.00; 95% CI 3.48–4.61; p < 0.001) after adjusting for confounding factors.
Conclusion: There is a significant association between depressive symptoms and daytime sleepiness, underscoring the need for a multifaceted approach to enhance sleep quality, alleviate depression symptoms, and manage comorbidities.
