Advances in Gene Therapy Treatment for Obesity: A Mini-review

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Paul Warncke
Natalia Oliveira
Tássia Medeiros Feldens
Guilherme L. da Rocha
Julia Daudt de Faro Salamonde
Veronica Echavarria
Daniela Ibanez F
Anthonia Inibokun Njoku
Roberto Nishimura
Javier Grajeda
Jose Laso
Sasha Mukhija
Antonia Egert
Magdiel A. Amell Castillo
Leticia Checo
Luana Moreira
Thaila Pereira Schmidt
Marcio Carlos de Freitas
Luciane Lie Ikeda
Ana Beatriz Pizarro

Abstract

Obesity is a highly prevalent global pandemic that is rapidly growing. Recent advancements in gene therapy have opened
new possibilities and targets for treating, especially monogenic forms of obesity. This mini-view identified novel preclinical
developments in obesity genetic treatment over the past five years. Novel strategies targeting single or multiple genes or
enzymes were identified as potential alternatives for existing treatment approaches. Although clinical trials for genetic
obesity treatment are yet to emerge, novel preclinical treatment approaches based on genetic traits hold promise for addressing
the obesity pandemic.

Article Details

How to Cite
Advances in Gene Therapy Treatment for Obesity: A Mini-review. (2024). Principles and Practice of Clinical Research, 9(4). https://doi.org/10.21801/ppcrj.2023.94.7
Section
View and Review

How to Cite

Advances in Gene Therapy Treatment for Obesity: A Mini-review. (2024). Principles and Practice of Clinical Research, 9(4). https://doi.org/10.21801/ppcrj.2023.94.7